Concepedia

Pedro Saavedra

PS

19

Publications

1.2K

Citations

14

H-Index

2010

Active since

Affiliations

VIB-UGent Center for Inflammation Research(Current)

Ghent University

Ghent University Hospital

Memorial Sloan Kettering Cancer Center

University of Edinburgh

Pedro Saavedra is an author at VIB-UGent Center for Inflammation Research specializing in medicine, cell biology, and cellular physiology.

ORCID

Top concepts

Publications per year

2010–2025

19

Publications

19

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever

Apurva Kanneganti, R. K. Subbarao Malireddi, Pedro Saavedra et al. · The Journal of Experimental Medicine · 2018 · 178 citations · Full text

Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation

Hanne Van Gorp, Pedro Saavedra, Nathalia M. de Vasconcelos et al. · Proceedings of the National Academy of Sciences · 2016 · 177 citations · Full text

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

Lieselotte Vande Walle, Irma B. Stowe, Pavel Šácha et al. · PLoS Biology · 2019 · 149 citations · Full text

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Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4

Nina Van Opdenbosch, Hanne Van Gorp, Maarten Verdonckt et al. · Cell Reports · 2017 · 128 citations · Full text

IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D

Máté Kiss, Lieselotte Vande Walle, Pedro Saavedra et al. · Cancer Immunology Research · 2020 · 91 citations · Full text

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