Pavel Šácha

PŠ

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Publications

Citations

1.5K

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Active since

2002

Affiliations

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry(Current)

Charles University

Czech Academy of Sciences

Czech Academy of Sciences, Institute of Macromolecular Chemistry

Czech Academy of Sciences, Institute of Molecular Genetics

Pavel Šácha is an author at Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry specializing in medicine, biochemistry, and natural sciences.

ORCID

Top concepts

MedicineBiochemistryNatural SciencesPharmacologyBiomolecular EngineeringProteomicsDrug DiscoveryCell BiologyMolecular BiologyImmunology

Publications per year

2002–2023

Publications

MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition

Lieselotte Vande Walle, Irma B. Stowe, Pavel Šácha et al. · PLoS Biology · 2019 · 149 citations · Full text

Immunology, Cell Death, Inflammation +16

Expression of glutamate carboxypeptidase II in human brain

Pavel Šácha, Cyril Bařinka, Klára Hlouchová et al. · Neuroscience · 2006 · 137 citations

Glutamate Carboxypeptidase Ii, Neurophysiology, Neurotransmitter +7

Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II

Cyril Bařinka, Markéta Rinnová, Pavel Šácha et al. · Journal of Neurochemistry · 2002 · 130 citations

Identification of the N‐glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity

Cyril Bařinka, Pavel Šácha, Jan Sklenář et al. · Protein Science · 2004 · 111 citations · Full text

Glycobiology, Molecular Biology, N‐glycosylation Sites +16

Fluorescent Nanodiamonds Embedded in Biocompatible Translucent Shells

Ivan Řehoř, Jitka Šlegerová, Jan Kučka et al. · Small · 2014 · 105 citations · Full text

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