Luca Prati

Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics

Laura Lucaroni, Tony Georgiev, Eleonora Prodi et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2022 · 39 citations

Undesired Salivary Gland, Signal Transduction, Biochemistry +7

Critical Evaluation of Photo-cross-linking Parameters for the Implementation of Efficient DNA-Encoded Chemical Library Selections

Alessandro Sannino, Adrián Gironda-Martínez, Émile M. D. Gorre et al. · ACS Combinatorial Science · 2020 · 37 citations

Engineering, Complementary Oligonucleotide, Molecular Biology +18

Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library

Sara Puglioli, Eleonore Schmidt, Christian Pellegrino et al. · Chem · 2022 · 37 citations

Drug Target, Novel Therapy, Drug Discovery +8

On-DNA hit validation methodologies for ligands identified from DNA-encoded chemical libraries

Luca Prati, Martina Bigatti, Etienne J. Donckèle et al. · Biochemical and Biophysical Research Communications · 2020 · 31 citations

Nucleic Acid Chemistry, Nucleic Acid Biomarkers, Biochemistry +12

A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition

Sebastian Oehler, Laura Lucaroni, Francesca Migliorini et al. · Nature Chemistry · 2023 · 28 citations

Chemical Biology, Nucleic Acid Chemistry, Biochemistry +11