Sara Puglioli

Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics

Laura Lucaroni, Tony Georgiev, Eleonora Prodi et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2022 · 41 citations

Medicine, Molecular Pharmaceutics, Nuclear Medicine +13

Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library

Sara Puglioli, Eleonore Schmidt, Christian Pellegrino et al. · Chem · 2022 · 41 citations

Pharmacy, Medicinal Chemistry, Oncology +16

A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition

Sebastian Oehler, Laura Lucaroni, Francesca Migliorini et al. · Nature Chemistry · 2023 · 33 citations

Pharmacy, Biochemistry, Biotechnology +12

Design and synthesis of the first indole-based blockers of Panx-1 channel

Letizia Crocetti, Gabriella Guerrini, Sara Puglioli et al. · European Journal of Medicinal Chemistry · 2021 · 18 citations · Full text

Natural Sciences, Medicinal Chemistry, Ion Channel Biophysics +8

Impact of library input on the hit discovery rate in DNA-encoded chemical library selections

Sara Puglioli, Sebastian Oehler, Luca Prati et al. · Chemical Science · 2023 · 10 citations · Full text

Pharmacy, Biotechnology, Drug Discovery +16