Christian Pellegrino

An ultra-high-affinity small organic ligand of fibroblast activation protein for tumor-targeting applications

Jacopo Millul, Gabriele Bassi, Jacqueline Mock et al. · Proceedings of the National Academy of Sciences · 2021 · 145 citations · Full text

Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications

Nicholas Favalli, Gabriele Bassi, Christian Pellegrino et al. · Nature Chemistry · 2021 · 72 citations · Full text

Dna Nanotechnology, Medicinal Chemistry, Engineering +9

Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics

Laura Lucaroni, Tony Georgiev, Eleonora Prodi et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2022 · 39 citations

Undesired Salivary Gland, Signal Transduction, Biochemistry +7

Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library

Sara Puglioli, Eleonore Schmidt, Christian Pellegrino et al. · Chem · 2022 · 37 citations

Drug Target, Novel Therapy, Drug Discovery +8

Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells

Chiara F. Magnani, Renier Myburgh, Silvan Brunn et al. · Molecular Therapy — Oncolytics · 2023 · 27 citations · Full text