Julie Blazel

Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors

Hui Li, John Tatlock, Angelica Linton et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +16

Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase

Frank Ruebsam, Douglas E. Murphy, Chinh Van Tran et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 43 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Allosteric Inhibitors of Hepatitis C Polymerase:  Discovery of Potent and Orally Bioavailable Carbon-Linked Dihydropyrones

Hui Li, Angelica Linton, John Tatlock et al. · Journal of Medicinal Chemistry · 2007 · 33 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase

Sun Hee Kim, Martin T. Tran, Frank Ruebsam et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

5,6-Dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase

Frank Ruebsam, Chinh Van Tran, Lian‐Sheng Li et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 29 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13