Masako Ura

Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue

Masanori Miwa, Masako Ura, M Nishida et al. · European Journal of Cancer · 1998 · 1.2K citations

Medicinal Chemistry, Cancer Tissue, Medicine +8

Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5?-deoxy-5-fluorouridine

Hiroyuki Eda, Kaori Fujimoto, Shinichi Watanabe et al. · Cancer Chemotherapy and Pharmacology · 1993 · 211 citations

Cancer Research, Cytokine, Oncogenic Agent +10

The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine

Nobuo Shimma, Isao UMEDA, M. Arasaki et al. · Bioorganic & Medicinal Chemistry · 2000 · 135 citations

Medicinal Chemistry, Polymer-drug Conjugate, Medicine +6

A Physiologically Based Pharmacokinetic Analysis of Capecitabine, a Triple Prodrug of 5-FU, in Humans: The Mechanism for Tumor-Selective Accumulation of 5-FU

Yuko Tsukamoto, Yukio Kato, Masako Ura et al. · Pharmaceutical Research · 2001 · 85 citations

Enhanced DNA synthesis of cultured vascular smooth muscle cells from spontaneously hypertensive rats Difference of response to growth factor, intracellular free calcium concentration and DNA synthesizing cell cycle

Masanori Hamada, Ichiro Nishio, Akira Baba et al. · Atherosclerosis · 1990 · 39 citations

Growth Factor, Enhanced Dna Synthesis, Physiology +8