Masako Ura

Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue

Masanori Miwa, Masako Ura, M Nishida et al. · European Journal of Cancer · 1998 · 1.2K citations

Medicine, Oncology, Pharmacology +12

Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5?-deoxy-5-fluorouridine

Hiroyuki Eda, Kaori Fujimoto, Shinichi Watanabe et al. · Cancer Chemotherapy and Pharmacology · 1993 · 211 citations

Medicine, Cancer Biology, Oncology +14

The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine

Nobuo Shimma, Isao UMEDA, M. Arasaki et al. · Bioorganic & Medicinal Chemistry · 2000 · 135 citations

Pharmacy, Medicinal Chemistry, Oncology +7

A Physiologically Based Pharmacokinetic Analysis of Capecitabine, a Triple Prodrug of 5-FU, in Humans: The Mechanism for Tumor-Selective Accumulation of 5-FU

Yuko Tsukamoto, Yukio Kato, Masako Ura et al. · Pharmaceutical Research · 2001 · 85 citations

Medicine, Pharmacokinetics, Pharmacology +15

Enhanced DNA synthesis of cultured vascular smooth muscle cells from spontaneously hypertensive rats Difference of response to growth factor, intracellular free calcium concentration and DNA synthesizing cell cycle

Masanori Hamada, Ichiro Nishio, Akira Baba et al. · Atherosclerosis · 1990 · 40 citations

Life Sciences, Molecular Biology, Calcium Homeostasis +12