Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons

Jason Schapansky, Saurabh Khasnavis, Mark P. DeAndrade, +7

Neurobiology of Disease

Neurodegenerative DiseasesMolecular NeuroscienceFamilial Knockin MutationSynaptic SignalingGenetic Disorder +10

Lysosome and Inflammatory Defects in <i>GBA1</i>‐Mutant Astrocytes Are Normalized by LRRK2 Inhibition

Anwesha Sanyal, Mark P. DeAndrade, Hailey S. Novis, +6

Movement Disorders

Motor restlessness, sleep disturbances, thermal sensory alterations and elevated serum iron levels in Btbd9 mutant mice

Mark P. DeAndrade, Russell L. Johnson, Erica L. Unger, +4

Human Molecular Genetics

Sleep DisordersSocial SciencesRls PatientsMotor RestlessnessNeurology +15

Characterization of Atp1a3 mutant mice as a model of rapid-onset dystonia with parkinsonism

Mark P. DeAndrade, Fumiaki Yokoi, Thomas van Groen, +2

Behavioural Brain Research

Atp1a3 Mutant MiceNeurodegenerative DiseasesMolecular NeurosciencePhysiologyDegenerative Disease +9

Altered Dendritic Morphology of Purkinje cells in Dyt1 ΔGAG Knock-In and Purkinje Cell-Specific Dyt1 Conditional Knockout Mice

Lin Zhang, Fumiaki Yokoi, Yuan‐Hu Jin, +4

PLoS ONE

Earlier onset of motor deficits in mice with double mutations in Dyt1 and Sgce

Fumiaki Yokoi, Guang Yang, JinDong Li, +3

The Journal of Biochemistry

Enhanced Hippocampal Long-Term Potentiation and Fear Memory in Btbd9 Mutant Mice

Mark P. DeAndrade, Li Zhang, Atbin Doroodchi, +6

PLoS ONE

Synaptic TransmissionNeurotransmitterAffective NeuroscienceNeurotransmissionSocial Sciences +20

The Role of BTBD9 in Striatum and Restless Legs Syndrome

Shangru Lyu, Hong Xing, Mark P. DeAndrade, +6

eNeuro

BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome

Shangru Lyu, Atbin Doroodchi, Hong Xing, +9

Brain Structure and Function

Neurological DisorderDopaminergic DysfunctionRestless LegsNeurologyNeuroscience +4

Hyperactivity, dopaminergic abnormalities, iron deficiency and anemia in an in vivo opioid receptors knockout mouse: Implications for the restless legs syndrome

Shangru Lyu, Mark P. DeAndrade, Stefan Müeller, +3

Behavioural Brain Research

NeurophysiologyMedicinePhysiologyNeuropharmacologyDopaminergic Abnormalities +9