Lysosome and Inflammatory Defects in <i>GBA1</i>‐Mutant Astrocytes Are Normalized by LRRK2 Inhibition

Anwesha Sanyal, Mark P. DeAndrade, Hailey S. Novis, +6

Movement Disorders

SARS-CoV-2 requires acidic pH to infect cells

Alex J.B. Kreutzberger, Anwesha Sanyal, Anand Saminathan, +18

Proceedings of the National Academy of Sciences

Novel assay reveals a large, inducible, replication-competent HIV-1 reservoir in resting CD4+ T cells

Anwesha Sanyal, Robbie B. Mailliard, Charles R. Rinaldo, +10

Nature Medicine

Replication-competent Hiv-1 ReservoirHuman RetrovirusImmunologyAntiviral ResponseVirology +7

LRRK2 Kinase Inhibition Rescues Deficits in Lysosome Function Due to Heterozygous GBA1 Expression in Human iPSC-Derived Neurons

Anwesha Sanyal, Hailey S. Novis, Emile Gasser, +2

Frontiers in Neuroscience

Synergistic Block of SARS-CoV-2 Infection by Combined Drug Inhibition of the Host Entry Factors PIKfyve Kinase and TMPRSS2 Protease

Alex J.B. Kreutzberger, Anwesha Sanyal, Ravi Ojha, +4

Journal of Virology

Deep neural network automated segmentation of cellular structures in volume electron microscopy

Benjamin Gallusser, Giorgio Maltese, Giuseppe Di Caprio, +7

The Journal of Cell Biology

EngineeringMicroscopyCytoskeletonBiomedical EngineeringElectron Microscopy +20

Human immunodeficiency virus infection induces lymphoid fibrosis in the BM-liver-thymus-spleen humanized mouse model

Jasmine Samal, Samantha Kelly, Ali Na-Shatal, +10

JCI Insight

Inherited nuclear pore substructures template post-mitotic pore assembly

Yi‐ying Chou, Srigokul Upadhyayula, Justin R. Houser, +10

Developmental Cell

Cell OrganelleMolecular BiologyStructural BiologyNuclear OrganizationCytoskeleton +4

Inhibitors of Signaling Pathways That Block Reversal of HIV-1 Latency

Benni Vargas, Nicholas S. Giacobbi, Anwesha Sanyal, +4

Antimicrobial Agents and Chemotherapy

Neuronal constitutive endolysosomal perforations enable α-synuclein aggregation by internalized PFFs

Anwesha Sanyal, Gustavo Scanavachi, Elliott Somerville, +8

The Journal of Cell Biology

Synaptic TransmissionMolecular BiologyCellular NeurobiologySynaptic SignalingSocial Sciences +20