Paul Kussie

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

Shiqing Li, Karl R. Schmitz, Philip D. Jeffrey et al. · Cancer Cell · 2005 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Immunology +7

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Douglas Burtrum, Zhenping Zhu, Dan Lu et al. · PubMed · 2003 · 349 citations

Human Growth, Immunology, Insulin Binding +17

Conservation of Structure and Mechanism between Eukaryotic Topoisomerase I and Site-Specific Recombinases

Chonghui Cheng, Paul Kussie, Nikola P. Pavletich et al. · Cell · 1998 · 234 citations · Full text

Chromatin, Natural Sciences, Eukaryotic Topoisomerase +8

Cloning and Functional Expression of a Human Heparanase Gene

Paul Kussie, Jeffrey D. Hulmes, Dale L. Ludwig et al. · Biochemical and Biophysical Research Communications · 1999 · 200 citations

Medicine, Genetics, Natural Sciences +9

High heparanase activity in multiple myeloma is associated with elevated microvessel density.

Thomas J. Kelly, Hua‐Quan Miao, Yang Yang et al. · PubMed · 2003 · 167 citations

Elevated Microvessel Density, Bone Marrow Plasma, Malignant Disease +15