Dan Lu

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Douglas Burtrum, Zhenping Zhu, Dan Lu et al. · PubMed · 2003 · 349 citations

Human Growth, Immunology, Insulin Binding +17

Therapeutic Implications of a Human Neutralizing Antibody to the Macrophage-Stimulating Protein Receptor Tyrosine Kinase (RON), a c-MET Family Member

Jennifer M. O'Toole, Karen E. Rabenau, Kerri Burns et al. · Cancer Research · 2006 · 120 citations

Immunology, Immunologic Mechanism, Immunotherapeutics +18

Potent neutralization of VEGF biological activities with a fully human antibody Fab fragment directed against VEGF receptor 2

Hua‐Quan Miao, Kun Hu, Xenia Jimenez et al. · Biochemical and Biophysical Research Communications · 2006 · 89 citations

Vegf Biological Activities, Angiogenesis, Human Growth +10

A recombinant, fully human, bispecific antibody neutralizes the biological activities mediated by both vascular endothelial growth factor receptors 2 and 3

Xenia Jimenez, Dan Lu, Laura Brennan et al. · Molecular Cancer Therapeutics · 2005 · 64 citations

Vegf Receptor 2, Immunology, Biological Activities +16

Suppression of leukemia expressing wild-type or ITD-mutant FLT3 receptor by a fully human anti-FLT3 neutralizing antibody

Yiwen Li, Hongli Li, Mei-Nai Wang et al. · Blood · 2004 · 53 citations · Full text