Xenia Jimenez

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Douglas Burtrum, Zhenping Zhu, Dan Lu et al. · PubMed · 2003 · 349 citations

Medicine, Oncology, Pharmacology +15

Tailoring in Vitro Selection for a Picomolar Affinity Human Antibody Directed against Vascular Endothelial Growth Factor Receptor 2 for Enhanced Neutralizing Activity

Dan Lü, Juqun Shen, Marie Danielle Vil et al. · Journal of Biological Chemistry · 2003 · 184 citations · Full text

Medicine, Molecular Biology, Oncology +17

Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity

Z Zhu, Koichi Hattori, H Zhang et al. · Leukemia · 2003 · 157 citations

Pharmacy, Oncology, Pharmacology +17

Anti-Vascular Endothelial Growth Factor Receptor-1 Antagonist Antibody as a Therapeutic Agent for Cancer

Yan Wu, Zhaojing Zhong, James Huber et al. · Clinical Cancer Research · 2006 · 151 citations

Medicine, Cancer Biology, Oncology +17

Monoclonal antibody cetuximab binds to and down-regulates constitutively activated epidermal growth factor receptor vIII on the cell surface.

Dipa Patel, Armin Lahiji, Sheetal Patel et al. · PubMed · 2007 · 150 citations

Medicine, Oncology, Pharmacology +17