Dale L. Ludwig

mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt

Kathryn O’Reilly, F. Rojo, Qing‐Bai She et al. · Cancer Research · 2006 · 2.6K citations · Full text

Medicine, Oncology, Pharmacology +16

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Douglas Burtrum, Zhenping Zhu, Dan Lu et al. · PubMed · 2003 · 349 citations

Medicine, Oncology, Pharmacology +15

The DNA Repair Endonuclease XPG Binds to Proliferating Cell Nuclear Antigen (PCNA) and Shares Sequence Elements with the PCNA-binding Regions of FEN-1 and Cyclin-dependent Kinase Inhibitor p21

Ronald K. Gary, Dale L. Ludwig, Helen L. Cornelius et al. · Journal of Biological Chemistry · 1997 · 237 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy

Danielle Ulanet, Dale L. Ludwig, C. Ronald Kahn et al. · Proceedings of the National Academy of Sciences · 2010 · 235 citations · Full text

Medicine, Endocrinology, Oncology +17

Physical Interaction between Human RAD52 and RPA Is Required for Homologous Recombination in Mammalian Cells

Min S. Park, Dale L. Ludwig, Evelyn Stigger et al. · Journal of Biological Chemistry · 1996 · 214 citations · Full text

Life Sciences, Genetics, Molecular Biology +16