Alexandra N. Newby

Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d

Namit Chaudhary, Lisa N. Kasiewicz, Alexandra N. Newby et al. · Nature Biomedical Engineering · 2024 · 75 citations · Full text

Lipid Preparation, Nanomedicine, Proteinlipid Interaction +9

The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology

John P. Gleeson, Katherine C. Fein, Namit Chaudhary et al. · International Journal of Pharmaceutics · 2020 · 35 citations · Full text

Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes

Namit Chaudhary, Alexandra N. Newby, Mariah L. Arral et al. · Proceedings of the National Academy of Sciences · 2024 · 34 citations · Full text

Nanoparticles, Engineering, Immunology +28

Branched‐Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice

Daria M. Strelkova Petersen, Ryan M. Weiss, Khalid A. Hajj et al. · Advanced Healthcare Materials · 2024 · 31 citations · Full text

Nanoparticles, Engineering, Lung Inflammation +17

Intestinal permeation enhancers enable oral delivery of macromolecules up to 70 kDa in size

Katherine C. Fein, John P. Gleeson, Alexandra N. Newby et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2021 · 30 citations · Full text

Gastrointestinal Peptide Hormone, Biochemistry, Medicine +13