Namit Chaudhary

The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs

Samuel T. LoPresti, Mariah L. Arral, Namit Chaudhary et al. · Journal of Controlled Release · 2022 · 237 citations · Full text

Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer

Jilian R. Melamed, Saigopalakrishna S. Yerneni, Mariah L. Arral et al. · Science Advances · 2023 · 168 citations · Full text

Nanotherapeutics, Engineering, Lipid Nanoparticles +18

A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing <i>In Vivo</i>

Khalid A. Hajj, Jilian R. Melamed, Namit Chaudhary et al. · Nano Letters · 2020 · 137 citations · Full text

Nanoparticles, Engineering, In Vivo Gene Therapy +17

Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery

Jilian R. Melamed, Khalid A. Hajj, Namit Chaudhary et al. · Journal of Controlled Release · 2021 · 82 citations · Full text

Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d

Namit Chaudhary, Lisa N. Kasiewicz, Alexandra N. Newby et al. · Nature Biomedical Engineering · 2024 · 75 citations · Full text

Lipid Preparation, Nanomedicine, Proteinlipid Interaction +9