Dominique Burger

Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations

G. Schoch, Brigitte D’Arcy, M. Stihle et al. · Journal of Molecular Biology · 2009 · 126 citations

Signal Transduction, Molecular Physiology, Biochemistry +14

DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome

Hans Richter, Alexander L. Satz, Marc Bedoucha et al. · ACS Chemical Biology · 2018 · 110 citations · Full text

Engineering of Phytase for Improved Activity at Low pH

Andrea Tomschy, Roland Brugger, Martin Lehmann et al. · Applied and Environmental Microbiology · 2002 · 100 citations · Full text

Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys

Rainer E. Martin, Johannes D. Aebi, Benoit Hornsperger et al. · Journal of Medicinal Chemistry · 2015 · 42 citations · Full text

Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib

U. Obst-Sander, Antônio Ricci, Bernd Kuhn et al. · Journal of Medicinal Chemistry · 2022 · 35 citations · Full text