Benoit Hornsperger

Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys

Rainer E. Martin, Johannes D. Aebi, Benoit Hornsperger et al. · Journal of Medicinal Chemistry · 2015 · 44 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model

Esther Melo, Philipp Oertle, Carolyn Trepp et al. · EBioMedicine · 2017 · 21 citations · Full text

Health Professions, Cell Biology, Ophthalmology +17

Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors

Yongfu Liu, Jun Wu, Mingwei Zhou et al. · Journal of Medicinal Chemistry · 2020 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold

Yingfang He, Adrienne Müller Herde, Didier Rombach et al. · Nuclear Medicine and Biology · 2022 · 18 citations · Full text

Medicine, Neuroscience, Pharmacology +16

A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature

Alicia M. Kemble, Benoit Hornsperger, Iris Ruf et al. · PLoS ONE · 2022 · 13 citations · Full text

Medicine, Neuroscience, Pharmacology +17