Johannes D. Aebi - Concepedia

Concepedia

Author

Johannes D. Aebi

Roche (Switzerland)

Also Known As

Aebi, J.D., Aebi, Johannes, Aebi, Johannes D., Aebi, Johannes Daniel, J Aebi, J D Aebi, J. Aebi, J. D. AEBI, J.D. Aebi, Johannes Aebi

65

Publications

1.9K

Citations

25

H-Index

59

Concepts

All Affiliations

Roche (Switzerland)ETH Zurich University of Lausanne University Hospital of Lausanne Roche (China)

JD

About

Johannes D. Aebi is an author at Roche (Switzerland) specializing in biochemistry, drug discovery, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Biochemistry	14	18	1.2K
2	Medicine	13	14	723
3	Natural Sciences	13	15	1.1K
4	Engineering	7	7	502
5	Biomolecular Engineering	6	6	487

Johannes D. Aebi

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36

Publications

1.9K

Citations

24

H-Index

	Year	Citations
Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase Ralf Thoma, Tanja Schulz‐Gasch, Brigitte D’Arcy, Nature BiosynthesisBioorganic ChemistryAldo-keto ReductaseBiochemistryHuman Oxidosqualene Cyclase	2004	347
Stereoselektive Alkylierung an C(α) von Serin, Glycerinsäure, Threonin und Weinsäure über heterocyclische Enolate mit exocyclischer Doppelbindung Dieter Seebàch, Johannes D. Aebi, Marlyse Gander‐Coquoz, Helvetica Chimica Acta EngineeringHeterocyclicBiochemistryNatural SciencesSteroselective Alkylation	1987	162
Ro 48-8.071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin O. Morand, Johannes D. Aebi, Henrietta Dehmlow, Journal of Lipid Research	1997	158
α-alkylation of serine with self-reproduction of the center of chirality Dieter Seebàch, Johannes D. Aebi Tetrahedron Letters Bioorganic ChemistryEngineeringBiochemistryNatural SciencesOrganic Chemistry	1984	125
α‐Alkylation of Amino Acids without Racemization. Preparation of Either (<i>S</i>)‐ or (<i>R</i>)‐α‐Methyldopa from (<i>S</i>)‐Alanine Dieter Seebàch, Johannes D. Aebi, Reto Naef, Helvetica Chimica Acta BiosynthesisBioorganic ChemistryAmino AcidsBiochemistryEngineering	1985	97
Enantioselektive α‐Alkylierung von Asparagin‐ und Glutaminsäure über die Dilithium‐enolatocarboxylate von 2‐[3‐Benzoyl‐2‐(<i>tert</i>‐butyl)‐1‐methyl‐5‐oxoimidazolidin‐4‐yl]essigsäure und 3‐[3‐Benzoyl‐2‐(<i>tert</i>‐butyl)‐1‐methyl‐5‐oxoimidazolidin‐4‐yl]propionsäure Johannes D. Aebi, Dieter Seebàch Helvetica Chimica Acta Bioorganic ChemistryGlutamic AcidBiochemistryCrystalline Products 14Natural Sciences	1985	79
Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors Zongxing Qiu, Bernd Kuhn, Johannes D. Aebi, ACS Medicinal Chemistry Letters Cell AutophagyMedicinal ChemistryProtein FunctionBiochemistryAtg8 Family Proteins	2016	66
Synthesis and Structure−Activity Studies of Novel Orally Active Non-Terpenoic 2,3-Oxidosqualene Cyclase Inhibitors Henrietta Dehmlow, Johannes D. Aebi, Synèse Jolidon, Journal of Medicinal Chemistry	2003	53
α-Alkylation of threonine Dieter Seebàch, Johannes D. Aebi Tetrahedron Letters Organic ChemistryEnantioselective SynthesisBiochemistry	1983	53
Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene−Hopene Cyclase Alexander Lenhart, D.J. Reinert, Johannes D. Aebi, Journal of Medicinal Chemistry Bioorganic ChemistryHomologous Squalene−hopene CyclaseChemical BiologyHuman EnzymePharmaceutical Chemistry	2003	47

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