Johannes D. Aebi

Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase

Ralf Thoma, Tanja Schulz‐Gasch, Brigitte D’Arcy et al. · Nature · 2004 · 347 citations

Biosynthesis, Bioorganic Chemistry, Aldo-keto Reductase +13

Stereoselektive Alkylierung an C(α) von Serin, Glycerinsäure, Threonin und Weinsäure über heterocyclische Enolate mit exocyclischer Doppelbindung

Dieter Seebàch, Johannes D. Aebi, Marlyse Gander‐Coquoz et al. · Helvetica Chimica Acta · 1987 · 162 citations

Engineering, Heterocyclic, Biochemistry +13

Ro 48-8.071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin

O. Morand, Johannes D. Aebi, Henrietta Dehmlow et al. · Journal of Lipid Research · 1997 · 158 citations · Full text

α-alkylation of serine with self-reproduction of the center of chirality

Dieter Seebàch, Johannes D. Aebi · Tetrahedron Letters · 1984 · 125 citations

Bioorganic Chemistry, Engineering, Biochemistry +7

α‐Alkylation of Amino Acids without Racemization. Preparation of Either (<i>S</i>)‐ or (<i>R</i>)‐α‐Methyldopa from (<i>S</i>)‐Alanine

Dieter Seebàch, Johannes D. Aebi, Reto Naef et al. · Helvetica Chimica Acta · 1985 · 97 citations

Biosynthesis, Bioorganic Chemistry, Amino Acids +15