A possible role for plasmalogens in protecting animal cells against photosensitized killing.

Raphael A. Zoeller, O. Morand, C R Raetz

Journal of Biological Chemistry

ImmunotoxicologyLipid PeroxidationImmunologyCell DeathRedox Biology +19

Disappearance of plasmalogens from membranes of animal cells subjected to photosensitized oxidation.

O. Morand, Raphael A. Zoeller, C R Raetz

Journal of Biological Chemistry

Ro 48-8.071, a new 2,3-oxidosqualene:lanosterol cyclase inhibitor lowering plasma cholesterol in hamsters, squirrel monkeys, and minipigs: comparison to simvastatin

O. Morand, Johannes D. Aebi, Henrietta Dehmlow, +4

Journal of Lipid Research

The pharmacokinetics and tissue distribution of the glucosylceramide synthase inhibitor miglustat in the rat

Alexander Treiber, O. Morand, Martine Clozel

Xenobiotica

Type 1Gaucher DiseasePharmacological StudyMedicinePhysiology +7

A rapid selection for animal cell mutants with defective peroxisomes

O. Morand, Lee‐Ann H. Allen, Raphael A. Zoeller, +1

Biochimica et Biophysica Acta (BBA) - General Subjects

Cell DivisionGeneticsRapid SelectionMutagenesisReactive Oxygen Specie +5

Binding Structures and Potencies of Oxidosqualene Cyclase Inhibitors with the Homologous Squalene−Hopene Cyclase

Alexander Lenhart, D.J. Reinert, Johannes D. Aebi, +3

Journal of Medicinal Chemistry

Bioorganic ChemistryHomologous Squalene−hopene CyclaseChemical BiologyHuman EnzymePharmaceutical Chemistry +14

Glucosylceramide synthase inhibition with lucerastat lowers globotriaosylceramide and lysosome staining in cultured fibroblasts from Fabry patients with different mutation types

Richard W.D. Welford, Andreas Mühlemann, Marco Garzotti, +5

Human Molecular Genetics

Lucerastat, an iminosugar with potential as substrate reduction therapy for glycolipid storage disorders: safety, tolerability, and pharmacokinetics in healthy subjects

Nicolas Guérard, O. Morand, Jasper Dingemanse

Orphanet Journal of Rare Diseases

Drug SafetyFabry DiseaseMg LucerastatHealthy SubjectsPharmacological Study +13

Influence of Intrauterine Malnutrition on Brain Development: Alteration of Myelination

J.M. Bourre, O. Morand, C. Chanez, +2

Neonatology

NutritionBrain DevelopmentFetal MedicineBrain NutritionEmbryology +17

In vivo incorporation of exogenous [1-14C]stearic acid into neurons and astrocytes

O. Morand, Nicole Baumann, J.M. Bourre

Neuroscience Letters

BiochemistryNeurophysiologyCellular NeuroscienceNeural Stem CellVivo Incorporation +9