Concepedia

Martine Clozel

MC

Statistics

Publications

106

Citations

9.1K

H-Index

54

Active since

1983

Affiliations

Roche (Switzerland)(Current)

Actelion (Switzerland)

Inserm

Martine Clozel is an author at Roche (Switzerland) specializing in pharmacology, medicine, and endothelin receptor antagonists.

Publications per year

1983–2019

106

Publications

106

Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist.

Martine Clozel, Volker Breu, Gillian A. Gray et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 668 citations

, , +15

Promotion of sleep by targeting the orexin system in rats, dogs and humans

Catherine Brisbare‐Roch, Jasper Dingemanse, Ralf Koberstein et al. · Nature Medicine · 2007 · 567 citations

, , +12

Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist

Martine Clozel, Volker Breu, Kaspar F. Burri et al. · Nature · 1993 · 529 citations

, , +9

The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo

Martine Clozel, Gillian A. Gray, Volker Breu et al. · Biochemical and Biophysical Research Communications · 1992 · 402 citations

, , +9

Pharmacology of Macitentan, an Orally Active Tissue-Targeting Dual Endothelin Receptor Antagonist

Marc Iglarz, Christoph A. Binkert, Keith Morrison et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 325 citations

, , +10

1–5 of 106