Ralf Koberstein

Promotion of sleep by targeting the orexin system in rats, dogs and humans

Catherine Brisbare‐Roch, Jasper Dingemanse, Ralf Koberstein et al. · Nature Medicine · 2007 · 564 citations

Animal Physiology, Sleep Disorders, Sleep +15

N-Glycine-sulfonamides as potent dual orexin 1/orexin 2 receptor antagonists

Hamed Aissaoui, Ralf Koberstein, Cornelia Zumbrunn et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 28 citations · Full text

Biochemistry, Functional Selectivity, Medicine +6

Tetrahydroisoquinolines as Orexin Receptor Antagonists: Strategies for Lead Optimization by Solution-Phase Chemistry

Ralf Koberstein, Alexander Treiber, Thierry Sifferlen et al. · CHIMIA International Journal for Chemistry · 2003 · 28 citations · Full text

Large Libraries, Bioorganic Chemistry, Lead Identification +18

Orexin Receptor Antagonism: A New Principle in Neuroscience

Christoph Boss, Catherine Brisbare‐Roch, François Jenck et al. · CHIMIA International Journal for Chemistry · 2008 · 27 citations · Full text

Sleep Disorders, Social Sciences, Sleep Medicine +20

Chiral organometallic reagents. Part XXV.1 The stereochemistry of the ring opening of cyclopropylallyllithium compounds

Reinhard W. Hoffmann, Ralf Koberstein · Journal of the Chemical Society Perkin Transactions 2 · 2000 · 18 citations

α-Durylhomoallyllithium Compounds 20, Engineering, Biochemistry +12