Concepedia

Iris Ruf

IR

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Publications

7

Citations

259

H-Index

7

Active since

2007

Affiliations

Roche (Switzerland)(Current)

Iris Ruf is an author at Roche (Switzerland) specializing in life sciences, pharmacology, and neuroscience.

Publications per year

2007–2024

7

Publications

7

Path mediation analysis reveals GBA impacts Lewy body disease status by increasing α-synuclein levels

Anna Lisa Gündner, Gonzalo Durán-Pacheco, Silke Zimmermann et al. · Neurobiology of Disease · 2018 · 70 citations · Full text

, , +15

A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence

Ming Jiang, Mirjam Huizenga, Jonah L. Wirt et al. · Nature Communications · 2023 · 52 citations · Full text

, , +16

Role of the autotaxin-lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity

Leona Ho, Anja Osterwald, Iris Ruf et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2019 · 43 citations · Full text

, , +16

Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct

Alexandra Gehrlein, Vinod Udayar, Nadia Anastasi et al. · Nature Communications · 2023 · 41 citations · Full text

, , +17

Metabolite Identification via LC‐SPE‐NMR‐MS of the In vitro Biooxidation Products of a Lead mGlu5 Allosteric Antagonist and Impact on the Improvement of Metabolic Stability in the Series

Simona Ceccarelli, Götz Schlotterbeck, Patrick Boissin et al. · ChemMedChem · 2007 · 22 citations

, , +17

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