Brian G. Hartl

Biochemical and cellular effects of c-Src kinase-selective pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors

Alan J. Kraker, Brian G. Hartl, Aneesa M. Amar et al. · Biochemical Pharmacology · 2000 · 139 citations · Full text

Biochemistry, Medicine, Natural Sciences +7

2-Substituted Aminopyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer Activity

S. KLUTCHKO, James M. Hamby, Diane H. Boschelli et al. · Journal of Medicinal Chemistry · 1998 · 130 citations · Full text

Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8<i>H</i>-pyrido[2,3-<i>d</i>]pyrimidines:  Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors

Diane H. Boschelli, Zhipei Wu, S. KLUTCHKO et al. · Journal of Medicinal Chemistry · 1998 · 84 citations · Full text

Combinatorial Chemistry, Bioorganic Chemistry, Pharmacotherapy +17

Modulation of histone acetylation by [4-(acetylamino)-N-(2-amino-phenyl) benzamide] in HCT-8 colon carcinoma.

Alan J. Kraker, Craig A. Mizzen, Brian G. Hartl et al. · PubMed · 2003 · 67 citations

Hct-8 Colon Carcinoma, Tumor Biology, Histone Deacetylase +14

3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and Related 2-Urea Derivatives Are Potent and Selective Inhibitors of the FGF Receptor-1 Tyrosine Kinase

Andrew M. Thompson, Cleo J. C. Connolly, James M. Hamby et al. · Journal of Medicinal Chemistry · 2000 · 46 citations · Full text

Selective Blocking, Bioorganic Chemistry, Drug Target +17