Judy Lucas

SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice.

Jennifer M. Golas, Kim Arndt, Carlo Etienne et al. · PubMed · 2003 · 414 citations

Medicine, Oncology, Pharmacology +17

Ammonia Derived from Glutaminolysis Is a Diffusible Regulator of Autophagy

Christina H. Eng, Ker Yu, Judy Lucas et al. · Science Signaling · 2010 · 343 citations

Life Sciences, Cell Biology, Microbiology +5

Biochemical, Cellular, and <i>In vivo</i> Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

Ker Yu, Lourdes Toral‐Barza, Celine Shi et al. · Cancer Research · 2009 · 330 citations

Medicine, Oncology, Pharmacology +13

Tumor Cells Chronically Treated with a Trastuzumab–Maytansinoid Antibody–Drug Conjugate Develop Varied Resistance Mechanisms but Respond to Alternate Treatments

Frank Loganzo, Xingzhi Tan, Matthew Sung et al. · Molecular Cancer Therapeutics · 2015 · 270 citations

Medicine, Immunology, Oncology +17

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

Christina H. Eng, Zuncai Wang, Diane Tkach et al. · Proceedings of the National Academy of Sciences · 2015 · 224 citations · Full text

Medicine, Oncology, Pharmacology +16