Stephen A. Margosiak

Broad Antitumor and Antiangiogenic Activities of AG3340, a Potent and Selective MMP Inhibitor Undergoing Advanced Oncology Clinical Trials

David R. Shalinsky, John Brekken, Helen Y. Zou et al. · Annals of the New York Academy of Sciences · 1999 · 237 citations

Implications for Chk1 Regulation: The 1.7 Å Crystal Structure of Human Cell Cycle Checkpoint Kinase Chk1

Ping Chen, Chun Luo, Yali Deng et al. · Cell · 2000 · 192 citations · Full text

Signal Transduction, å Crystal Structure, Cell Division +8

Structure-Based Design, Synthesis, and Antimicrobial Activity of Indazole-Derived SAH/MTA Nucleosidase Inhibitors

Xiaoming Li, Sam Chu, Victoria A. Feher et al. · Journal of Medicinal Chemistry · 2003 · 160 citations · Full text

Core Scaffold, Combinatorial Chemistry, Medicinal Chemistry +14

Structure of the Human Cytomegalovirus Protease Catalytic Domain Reveals a Novel Serine Protease Fold and Catalytic Triad

Ping Chen, Hideaki Tsuge, Robert J. Almassy et al. · Cell · 1996 · 150 citations · Full text

Virus Structure, Biochemistry, Protein Folding +7

Structure-based design of novel human Pin1 inhibitors (I)

Chuangxing Guo, Xinjun Hou, Liming Dong et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 105 citations · Full text

Molecular Docking, Drug Target, Medicine +4