Structure of the Human Cytomegalovirus Protease Catalytic Domain Reveals a Novel Serine Protease Fold and Catalytic Triad

Ping Chen, Hideaki Tsuge, Robert J. Almassy, +7

Cell

Virus StructureBiochemistryProtein FoldingNatural SciencesMolecular Biology +5

A Simple HPLC Method for the Determination of S-Adenosylmethionine and S-Adenosylhomocysteine in Rat Tissues: The Effect of Vitamin B6 Deficiency on These Concentrations in Rat Liver

Qing‐Bai She, Itsuma Nagao, T. Hayakawa, +1

Biochemical and Biophysical Research Communications

HepatologyBiochemistryMedicineLiver PhysiologyPhysiology +11

Structural basis of actin recognition and arginine ADP-ribosylation by <i>Clostridium perfringens</i> ι-toxin

Hideaki Tsuge, Masahiro Nagahama, Masataka Oda, +6

Proceedings of the National Academy of Sciences

Crystal StructureProtein AssemblyBacteriologyActin-specific AdprtsMolecular Biology +16

Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo

Nobuhiko Katunuma, E. Murata, Hisao Kakegawa, +7

FEBS Letters

Crystal Structure and Site-directed Mutagenesis of Enzymatic Components from Clostridium perfringens Iota-toxin

Hideaki Tsuge, Masahiro Nagahama, Hiroyuki Nishimura, +5

Journal of Molecular Biology

Enzymatic ComponentsCrystal StructureMicrobial ToxinToxinologyProtein X-ray Crystallography +4

Crystal structure of human D‐amino acid oxidase: Context‐dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the <i>si</i>‐face of the flavin ring

Tomoya Kawazoe, Hideaki Tsuge, Mirella S. Pilone, +1

Protein Science

Crystal StructureMolecular BiologyChemical BiologyProtein X-ray CrystallographyHuman Dao +18

Inhibition Mechanism of Cathepsin L-Specific Inhibitors Based on the Crystal Structure of Papain–CLIK148 Complex

Hideaki Tsuge, Tomohiro Nishimura, Yukio Tada, +3

Biochemical and Biophysical Research Communications

Crystal StructureInhibition MechanismBiochemistryCathepsin L-specific InhibitorsMedicine +5

Structural Basis of the Influenza A Virus RNA Polymerase PB2 RNA-binding Domain Containing the Pathogenicity-determinant Lysine 627 Residue

Takashi Kuzuhara, Daisuke Kise, Hiroko Yoshida, +6

Journal of Biological Chemistry

Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus

Hideo Ago, Masataka Oda, Masaya Takahashi, +5

Journal of Biological Chemistry

Neutral SphingomyelinaseCrystal StructureSignal TransductionCellular EnzymologyBiochemistry +10

Identification of 16 novel mutations in the argininosuccinate synthetase gene and genotype-phenotype correlation in 38 classical citrullinemia patients

Hong‐Zhi Gao, Keiko Kobayashi, Ayako Tabata, +33

Human Mutation

Argininosuccinate Synthetase GeneClassical Citrullinemia PatientsGenetic DisorderGeneticsAss Mutations +13