Ai Ching Wong

Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance

Diana Zatreanu, Helen M.R. Robinson, Omar Alkhatib et al. · Nature Communications · 2021 · 336 citations · Full text

Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets

Matthias G. J. Baud, Thomas Leiser, Patricia Haus et al. · Journal of Medicinal Chemistry · 2012 · 96 citations · Full text

Drug Target, Epigenetic Change, Molecular Biology +20

Crystal structure of human CDC7 kinase in complex with its activator DBF4

Siobhan Hughes, Frédéric Elustondo, Andrea Di Fonzo et al. · Nature Structural & Molecular Biology · 2012 · 75 citations

Crystal Structure, Protein Function, Human Cdc7 Kinase +7

Identification of 3-aminothieno[2,3-b]pyridine-2-carboxamides and 4-aminobenzothieno[3,2-d]pyrimidines as LIMK1 inhibitors

Brad E. Sleebs, Alla Levit, Ian P. Street et al. · MedChemComm · 2011 · 24 citations

Combinatorial Chemistry, Medicinal Chemistry, Bicyclic Hits +14

Development of a High-Throughput Screening Method for LIM Kinase 1 Using a Luciferase-Based Assay of ATP Consumption

Mokdad Mezna, Ai Ching Wong, Margaret Ainger et al. · SLAS DISCOVERY · 2011 · 18 citations · Full text