Patricia Haus

Defining the Mechanism of Action and Enzymatic Selectivity of Psammaplin A against Its Epigenetic Targets

Matthias G. J. Baud, Thomas Leiser, Patricia Haus et al. · Journal of Medicinal Chemistry · 2012 · 96 citations · Full text

Drug Target, Epigenetic Change, Molecular Biology +20

Highly Ligand Efficient and Selective <i>N</i>‐2‐(Thioethyl)picolinamide Histone Deacetylase Inhibitors Inspired by the Natural Product Psammaplin A

Matthias G. J. Baud, Patricia Haus, Thomas Leiser et al. · ChemMedChem · 2012 · 19 citations

Non-isotopic dual parameter competition assay suitable for high-throughput screening of histone deacetylases

Daniel Riester, Christian Hildmann, Patricia Haus et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 18 citations · Full text

Chromatin, Histone Deacetylases, Biochemistry +13

Identification of Selective Class II Histone Deacetylase Inhibitors Using a Novel Dual-Parameter Binding Assay Based on Fluorescence Anisotropy and Lifetime

Patricia Haus, Michael Korbus, Michael Schröder et al. · SLAS DISCOVERY · 2011 · 12 citations · Full text

Chromatin, Medicinal Chemistry, Histone Deacetylases +13

Synthesis and biochemical analysis of 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-octanediamides as inhibitors of human histone deacetylases

Leonhard M. Henkes, Patricia Haus, Felix Jäger et al. · Bioorganic & Medicinal Chemistry · 2011 · 11 citations · Full text

Medicinal Chemistry, Natural Product Synthesis, Derivative (Chemistry) +10