A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Michal Slyper, Caroline Porter, Orr Ashenberg, +47

Nature Medicine

Orthotopic patient-derived xenografts of paediatric solid tumours

Elizabeth Stewart, Sara M. Federico, Xiang Chen, +22

Nature

MedicineOrthotopic Patient-derived XenograftsRadiopharmaceutical TherapyOncologyRadiation Oncology +1

Targeting the DNA Repair Pathway in Ewing Sarcoma

Elizabeth Stewart, Ross Goshorn, Cori Bradley, +22

Cell Reports

Novel Strategy to Prevent Otitis Media Caused by Colonizing Streptococcus pneumoniae

Jonathan A. McCullers, Åsa Karlström, Amy Iverson, +2

PLoS Pathogens

Microbial PathogensAntibiotic AdjuvantPrevent Otitis MediaBacterial PathogensDrug Resistance +17

Treatment with Protein Synthesis Inhibitors Improves Outcomes of Secondary Bacterial Pneumonia after Influenza

Åsa Karlström, Kelli L. Boyd, B. Keith English, +1

The Journal of Infectious Diseases

Toll-Like Receptor 2 Mediates Fatal Immunopathology in Mice During Treatment of Secondary Pneumococcal Pneumonia Following Influenza

Åsa Karlström, Sarah M. Heston, Kelli L. Boyd, +2

The Journal of Infectious Diseases

Mediates Fatal ImmunopathologyMicrobial PathogensLung InflammationInnate Immune SystemImmunology +19

The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities

Elizabeth Stewart, Sara M. Federico, Åsa Karlström, +4

Developmental Biology

PathologyPediatric Solid TumorsPediatric Solid TumorCancer BiologyTumor Biology +16

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma

Ankita Gupte, Emma K. Baker, Soo-San Wan, +17

Clinical Cancer Research

A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors

Michal Slyper, Caroline Porter, Orr Ashenberg, +44

The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma

Anand G. Patel, Xiang Chen, Xin Huang, +17

Developmental Cell

Malignant DiseaseOncogenic AgentGeneticsMyogenesis ProgramClonal Selection +5