Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

Christopher S. Smillie, Moshe Biton, José Ordovás-Montañés, +30

Cell

InflammationMucosal ImmunologyImmunologyGastroenterologyPathology +8

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

Daniel T. Montoro, Adam L. Haber, Moshe Biton, +26

Nature

Pulmonary PhysiologyCftr-expressing IonocytesMedicineCell BiologyCellular Physiology +1

COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

Toni Delorey, Carly G.K. Ziegler, Graham Heimberg, +105

Nature

Covid-19 Tissue AtlasesCovid-19 PandemicPathologyVirologyCovid-19 Epidemiology +2

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Michal Slyper, Caroline Porter, Orr Ashenberg, +47

Nature Medicine

Decoding human fetal liver haematopoiesis

Dorin-Mirel Popescu, Rachel A. Botting, Emily Stephenson, +53

Nature

Developmental BiologyHepatologyXenotransplantationLiver PhysiologyFetal Medicine +6

Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus

Richard K. Perez, M. Grace Gordon, Meena Subramaniam, +26

Science

A single-cell landscape of high-grade serous ovarian cancer

Benjamin Izar, Itay Tirosh, Elizabeth H. Stover, +31

Nature Medicine

Tumor HeterogeneityMedicineGynecologySingle-cell LandscapeOncology +3

Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function

Gökçen Eraslan, Eugene Drokhlyansky, Shankara Anand, +23

Science

GeneticsGene ModulesGenetic EpidemiologyMultiomicsGene Characterization +18

Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems

Shahar Alon, Daniel Goodwin, Anubhav Sinha, +116

Science

snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis

Wenfei Sun, Hua Dong, Miroslav Baláž, +15

Nature

Energy HomeostasisDevelopmental BiologySnrna-seq RevealsGene RegulationMetabolic Regulation +3