Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma

Xiang Chen, Elizabeth Stewart, Anang A. Shelat, +43

Cancer Cell

Reductive StressReactive Oxygen SpecieMedicineCell BiologyRedox Biology +1

Orthotopic patient-derived xenografts of paediatric solid tumours

Elizabeth Stewart, Sara M. Federico, Xiang Chen, +22

Nature

MedicineOrthotopic Patient-derived XenograftsRadiopharmaceutical TherapyOncologyRadiation Oncology +1

Targeting the DNA Repair Pathway in Ewing Sarcoma

Elizabeth Stewart, Ross Goshorn, Cori Bradley, +22

Cell Reports

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses

Elizabeth Stewart, Justina McEvoy, Hong Wang, +35

Cancer Cell

Systems BiologyFunctional GenomicsEngineeringTumor HeterogeneityProteomic Analyses +11

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Maged Zeineldin, Sara M. Federico, Xiang Chen, +33

Nature Communications

ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures

Zulekha A. Qadeer, David Valle‐García, Dan Hasson, +28

Cancer Cell

Ezh2 InhibitionNeuro-oncologyMolecular NeuroscienceGliomaNeuronal Gene Signatures +6

Retinoblastoma from human stem cell-derived retinal organoids

Jacqueline L. Norrie, Anjana Nityanandam, Karen Lai, +16

Nature Communications

Tumor BiologyInduced Pluripotent Stem CellOcular DiseaseDevelopmental BiologyRetina +13

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma

Min Pan, William C. Wright, Richard H. Chapple, +27

Nature Communications

A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma

Wayne L. Furman, Sara M. Federico, M. Beth McCarville, +21

Clinical Cancer Research

Pediatric Brain TumorsImmunologyPathologyImmunotherapeuticsHigh-grade Gliomas +16

BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action

Nathaniel Twarog, Elizabeth Stewart, Courtney Vowell Hammill, +1

Scientific Reports