Brent Bowden

Studying multisite binary and ternary protein interactions by global analysis of isothermal titration calorimetry data in SEDPHAT: Application to adaptor protein complexes in cell signaling

Jon C. D. Houtman, Patrick H. Brown, Brent Bowden et al. · Protein Science · 2006 · 338 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1

Jon C. D. Houtman, Hiroshi Yamaguchi, Mira Barda‐Saad et al. · Nature Structural & Molecular Biology · 2006 · 219 citations

Life Sciences, Biochemistry, Molecular Biology +12

Binding Specificity of Multiprotein Signaling Complexes Is Determined by Both Cooperative Interactions and Affinity Preferences

Jon C. D. Houtman, Yuichiro Higashimoto, Nazzareno Dimasi et al. · Biochemistry · 2004 · 111 citations

Life Sciences, Biochemistry, Molecular Biology +17