Concepedia

Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1

Jon C. D. Houtman, Hiroshi Yamaguchi, Mira Barda‐Saad, Alex Braiman, Brent Bowden, Ettore Appella, Peter Schuck, Lawrence E. Samelson

Nature Structural & Molecular Biology · 2006 · 219 citations · 30 references

DOI

Concepts

References

30

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

Peter Schuck · Biophysical Journal · 2000 · 4K citations · Full text

, , +10

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

Sean E. Egan, B.W. Giddings, Mary W. Brooks et al. · Nature · 1993 · 1.2K citations

, , +14

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

Maria Rozakis-Adcock, Ross T. Fernley, John D. Wade et al. · Nature · 1993 · 1K citations

, , +17

Human Sos1: a Guanine Nucleotide Exchange Factor for Ras that Binds to GRB2

Pierre Teilhard de Chardin, Jacques Camonis, Nicholas W. Gale et al. · Science · 1993 · 800 citations

, , +17

Protein–protein interactions define specificity in signal transduction

Tony Pawson, Piers Nash · Genes & Development · 2000 · 779 citations · Full text

, , +14