Jon C. D. Houtman

NetPath: a public resource of curated signal transduction pathways

Kumaran Kandasamy, S Sujatha Mohan, Rajesh Raju et al. · Genome biology · 2010 · 527 citations · Full text

Environmental Signaling, Engineering, Immunology +18

Studying multisite binary and ternary protein interactions by global analysis of isothermal titration calorimetry data in SEDPHAT: Application to adaptor protein complexes in cell signaling

Jon C. D. Houtman, Patrick H. Brown, Brent Bowden et al. · Protein Science · 2006 · 334 citations · Full text

Signal Transduction, Biochemistry, Protein Assembly +15

Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1

Jon C. D. Houtman, Hiroshi Yamaguchi, Mira Barda‐Saad et al. · Nature Structural & Molecular Biology · 2006 · 215 citations

Signal Transduction, Signaling Pathway, Protein Assembly +10

Binding Specificity of Multiprotein Signaling Complexes Is Determined by Both Cooperative Interactions and Affinity Preferences

Jon C. D. Houtman, Yuichiro Higashimoto, Nazzareno Dimasi et al. · Biochemistry · 2004 · 111 citations

Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters

Alessandra Picollo, Mattia Malvezzi, Jon C. D. Houtman et al. · Nature Structural & Molecular Biology · 2009 · 110 citations · Full text

Proteinlipid Interaction, Substrate Binding, Molecular Physiology +11