Paul Blaney

Discovery of Novel PI3-Kinase δ Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition

Brian S. Safina, Stewart Baker, Matt Baumgardner et al. · Journal of Medicinal Chemistry · 2012 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Potent and selective inhibitors of PI3Kδ: Obtaining isoform selectivity from the affinity pocket and tryptophan shelf

Daniel P. Sutherlin, Stewart Baker, Angelina Bisconte et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity

Robin D. Clark, Nicholas C. Ray, Karen Williams et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 49 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Solid-phase synthesis of diverse tetrahydro-1,4-benzodiazepine-2-ones

Gurdip Bhalay, Paul Blaney, Vanessa H. Palmer et al. · Tetrahedron Letters · 1997 · 35 citations

Pharmacy, Chemistry, Medicinal Chemistry +13

Fused and bridged bi- and tri-cyclic lactams via sequential metallo-azomethine ylide cycloaddition–lactamisation

Paul Blaney, Ronald Grigg, Zoran Ranković et al. · Tetrahedron · 2002 · 31 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8