Concepedia

1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity

Robin D. Clark, Nicholas C. Ray, Karen Williams, Paul Blaney, Stuart D.C. Ward, Peter H. Crackett, Christopher A. Hurley, Hazel J. Dyke, David E. Clark, Peter Lockey,

Bioorganic & Medicinal Chemistry Letters · 2008 · 49 citations · 13 references

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References

13

Enantioselective synthesis of quaternary carbon centers through Michael-type alkylation of chiral imines

Michel Pfau, Gilbert Revıal, André Guingant et al. · Journal of the American Chemical Society · 1985 · 211 citations

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Clinical and Biological Effects of Mifepristone Treatment for Psychotic Depression

Benjamin Flores, Heather A. Kenna, Jennifer Keller et al. · Neuropsychopharmacology · 2005 · 204 citations · Full text

, , +14

Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands

Nilesh Shah, Thomas S. Scanlan · Bioorganic & Medicinal Chemistry Letters · 2004 · 80 citations · Full text

, , +12

Discovery of Potent, Nonsteroidal, and Highly Selective Glucocorticoid Receptor Antagonists

B. Paul Morgan, Andrew G. Swick, Diane M. Hargrove et al. · Journal of Medicinal Chemistry · 2002 · 60 citations · Full text

, , +17

<b>Synthesis and Structure of Steroidal 4-Pregneno [3,2-<b><i>c</i></b>]Pyrazoles. A Novel Class of Potent Anti-Inflammatory Steroids</b>

Ralph Hirschmann, N. G. Steinberg, Paul Buchschacher et al. · Journal of the American Chemical Society · 1963 · 57 citations

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