Diane M. Hargrove

Isozyme-nonselective N-Substituted Bipiperidylcarboxamide Acetyl-CoA Carboxylase Inhibitors Reduce Tissue Malonyl-CoA Concentrations, Inhibit Fatty Acid Synthesis, and Increase Fatty Acid Oxidation in Cultured Cells and in Experimental Animals

H. James Harwood, Stephen F. Petras, Lorraine D. Shelly et al. · Journal of Biological Chemistry · 2003 · 243 citations · Full text

Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TRβ subtype-selective thyromimetics

Robert L. Dow, Steven R. Schneider, Ernest S. Paight et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 93 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Novel Series +7

Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodents

Krystyna Tatarkiewicz, Pam Smith, Emmanuel J. Sablan et al. · American Journal of Physiology-Endocrinology and Metabolism · 2010 · 91 citations · Full text

Gastrointestinal Pharmacology, Immunology, Gastroenterology +17

GLUT4 Overexpression in <i>db/db</i> Mice Dose-Dependently Ameliorates Diabetes But Is Not a Lifelong Cure

Joseph T. Brozinick, Scott C. McCoid, Thomas Reynolds et al. · Diabetes · 2001 · 76 citations · Full text

Lifelong Cure, Glut4 Overexpression, Immunology +20

Discovery of Potent, Nonsteroidal, and Highly Selective Glucocorticoid Receptor Antagonists

B. Paul Morgan, Andrew G. Swick, Diane M. Hargrove et al. · Journal of Medicinal Chemistry · 2002 · 60 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +13