Peter H. Crackett

Studies toward the Large-Scale Synthesis of the HIV Proteinase Inhibitor Ro 31-8959

K. E. B. PARKES, D. J. BUSHNELL, Peter H. Crackett et al. · The Journal of Organic Chemistry · 1994 · 98 citations

Altmetric Attention Score, Peptide Science, Antiviral Drug +19

Identification of <i>C</i>-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2

Mark Zak, Christopher A. Hurley, Stuart I. Ward et al. · Journal of Medicinal Chemistry · 2013 · 61 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Chemical Biology +19

Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling

Mark Zak, Emily J. Hanan, Patrick J. Lupardus et al. · Bioorganic & Medicinal Chemistry Letters · 2019 · 52 citations · Full text

Effective Cell-based Blockade, Signaling Pathway, Novel Therapy +9

Asymmetric synthesis via acetal templates. 9. Further studies of the allylation reaction. Preparation of (−)-dihydromyoporone

William S. Johnson, Peter H. Crackett, John D. Elliott et al. · Tetrahedron Letters · 1984 · 50 citations

Cross-coupling Reaction, Engineering, Asymmetric Synthesis +9

1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity

Robin D. Clark, Nicholas C. Ray, Karen Williams et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 49 citations · Full text

Selective Glucocorticoid Receptor, Biochemistry, Functional Selectivity +6