Jörn Weisner

Covalent‐Allosteric Kinase Inhibitors

Jörn Weisner, Rajesh Gontla, Leandi Van Der Westhuizen et al. · Angewandte Chemie International Edition · 2015 · 112 citations

Molecular Docking, Molecular Pharmacology, Medicinal Chemistry +15

Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in <i>KRAS</i>-Mutant Pancreatic and Colorectal Cancer

Jörn Weisner, Ina Landel, Christoph Reintjes et al. · Cancer Research · 2019 · 88 citations

2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach

Miriam Schehr, Chiara Lanes, Jörn Weisner et al. · Photochemical & Photobiological Sciences · 2019 · 73 citations

Photoswitchable Kinase Inhibitors, Photochromism, Photochemistry +10

Covalent‐Allosteric Inhibitors to Achieve Akt Isoform‐Selectivity

Lena Quambusch, Ina Landel, Laura Depta et al. · Angewandte Chemie International Edition · 2019 · 69 citations · Full text

Molecular Docking, Molecular Pharmacology, Medicinal Chemistry +15

Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt

Niklas Uhlenbrock, Steven P. Smith, Jörn Weisner et al. · Chemical Science · 2019 · 65 citations · Full text

Molecular Biology, Chemical Biology, Pharmaceutical Chemistry +18