Concepedia

Lena Quambusch

LQ

Statistics

Publications

7

Citations

376

H-Index

7

Active since

2017

Affiliations

TU Dortmund University(Current)

German Cancer Research Center

Heidelberg University

Lead Discovery Center (Germany)

Deutsches Konsortium für Translationale Krebsforschung

Lena Quambusch is an author at TU Dortmund University specializing in ligand binding, medicinal chemistry, and drug discovery.

ORCID

Publications per year

2017–2021

7

Publications

7

Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in <i>KRAS</i>-Mutant Pancreatic and Colorectal Cancer

Jörn Weisner, Ina Landel, Christoph Reintjes et al. · Cancer Research · 2019 · 91 citations

, , +17

Covalent‐Allosteric Inhibitors to Achieve Akt Isoform‐Selectivity

Lena Quambusch, Ina Landel, Laura Depta et al. · Angewandte Chemie International Edition · 2019 · 71 citations · Full text

, , +17

Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt

Niklas Uhlenbrock, Steven P. Smith, Jörn Weisner et al. · Chemical Science · 2019 · 70 citations · Full text

, , +17

Cellular model system to dissect the isoform-selectivity of Akt inhibitors

Lena Quambusch, Laura Depta, Ina Landel et al. · Nature Communications · 2021 · 54 citations · Full text

, , +16

Spotlight on AKT: Current Therapeutic Challenges

Ina Landel, Lena Quambusch, Laura Depta et al. · ACS Medicinal Chemistry Letters · 2020 · 52 citations · Full text

, , +17

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