Laura Depta

Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in <i>KRAS</i>-Mutant Pancreatic and Colorectal Cancer

Jörn Weisner, Ina Landel, Christoph Reintjes et al. · Cancer Research · 2019 · 88 citations

Covalent‐Allosteric Inhibitors to Achieve Akt Isoform‐Selectivity

Lena Quambusch, Ina Landel, Laura Depta et al. · Angewandte Chemie International Edition · 2019 · 69 citations · Full text

Molecular Docking, Molecular Pharmacology, Medicinal Chemistry +15

Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt

Niklas Uhlenbrock, Steven P. Smith, Jörn Weisner et al. · Chemical Science · 2019 · 65 citations · Full text

Molecular Biology, Chemical Biology, Pharmaceutical Chemistry +18

Spotlight on AKT: Current Therapeutic Challenges

Ina Landel, Lena Quambusch, Laura Depta et al. · ACS Medicinal Chemistry Letters · 2020 · 52 citations · Full text

Apoptosis, Immunology, Cell Death +22

Cellular model system to dissect the isoform-selectivity of Akt inhibitors

Lena Quambusch, Laura Depta, Ina Landel et al. · Nature Communications · 2021 · 50 citations · Full text