Concepedia

Patrick Strout

PS

7

Publications

360

Citations

7

H-Index

2013

Active since

Affiliations

AstraZeneca (Germany)(Current)

Spirogen (United Kingdom)

Patrick Strout is an author at AstraZeneca (Germany) specializing in drug discovery, antibody engineering, and medicine.

Top concepts

Publications per year

2013–2019

7

Publications

7

Antibody–Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies

Jonathan Rios‐Doria, Jay Harper, Raymond Rothstein et al. · Cancer Research · 2017 · 124 citations

Rational design, biophysical and biological characterization of site-specific antibody-tubulysin conjugates with improved stability, efficacy and pharmacokinetics

Pamela Thompson, Ryan Fleming, Binyam Bezabeh et al. · Journal of Controlled Release · 2016 · 59 citations

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Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody–Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer

Song Cho, Francesca Zammarchi, David G. Williams et al. · Molecular Cancer Therapeutics · 2018 · 46 citations

Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody–Drug Conjugate Targeting 5T4

Jay Harper, Christopher Lloyd, Nazzareno Dimasi et al. · Molecular Cancer Therapeutics · 2017 · 45 citations · Full text

Selecting an Optimal Antibody for Antibody–Drug Conjugate Therapy: Internalization and Intracellular Localization

Jay Harper, Shenlan Mao, Patrick Strout et al. · Methods in molecular biology · 2013 · 37 citations

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