Christopher Lloyd

A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope

Michael D. Miller, Romas Geleziunas, Elisabetta Bianchi et al. · Proceedings of the National Academy of Sciences · 2005 · 156 citations

Pharmacy, Immunology, Molecular Biology +17

Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens

Christopher Lloyd, David C. Lowe, Bryan Edwards et al. · Protein Engineering Design and Selection · 2008 · 130 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo

Claire Dobson, Paul W. A. Devine, Jonathan J. Phillips et al. · Scientific Reports · 2016 · 123 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo

Darren J. Schofield, Lorraine Irving, Laura Calò et al. · Neurobiology of Disease · 2019 · 119 citations · Full text

Life Sciences, Neurology, Neuroscience +17

A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma

E. Suzanne Cohen, Claire Dobson, Helena Käck et al. · mAbs · 2014 · 52 citations · Full text

Pharmacy, Immunology, Pharmacology +17