Guosen Ye

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang et al. · Nature · 2018 · 803 citations

Systemic Activity, Medicine, Mechanism Of Action +4

An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure

Kevin S. Thorneloe, Mui Cheung, Weike Bao et al. · Science Translational Medicine · 2012 · 328 citations

TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury

Shrilatha Balakrishna, Weifeng Song, Satyanarayana Achanta et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2014 · 199 citations · Full text

Acute Lung Injury, Asthma, Inflammatory Lung Disease +19

Development of Dihydropyridone Indazole Amides as Selective Rho-Kinase Inhibitors

Krista Goodman, Haifeng Cui, Sarah E. Dowdell et al. · Journal of Medicinal Chemistry · 2006 · 154 citations · Full text

Indazole Substitution, Medicinal Chemistry, Oral Bioavailability +11

Discovery of GSK2193874: An Orally Active, Potent, and Selective Blocker of Transient Receptor Potential Vanilloid 4

Mui Cheung, Weike Bao, David J. Behm et al. · ACS Medicinal Chemistry Letters · 2017 · 94 citations · Full text