Kevin S. Thorneloe

A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice

Dongeun Huh, Daniel C. Leslie, Benjamin D. Matthews et al. · Science Translational Medicine · 2012 · 988 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

N-((1 S)-1-{[4-((2 S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part I

Kevin S. Thorneloe, Anthony C. Sulpizio, Zuojun Lin et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 404 citations

Medicine, Pharmacology, Physiology +16

Overactive Bladder and Incontinence in the Absence of the BK Large Conductance Ca2+-activated K+ Channel

Andrea L. Meredith, Kevin S. Thorneloe, Matthias Werner et al. · Journal of Biological Chemistry · 2004 · 350 citations · Full text

Medicine, Physiology, Urology +12

An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure

Kevin S. Thorneloe, Mui Cheung, Weike Bao et al. · Science Translational Medicine · 2012 · 336 citations

Medicine, Cardiology, Pharmacotherapy +10

Systemic Activation of the Transient Receptor Potential Vanilloid Subtype 4 Channel Causes Endothelial Failure and Circulatory Collapse: Part 2

Robert N. Willette, Weike Bao, Sandhya S. Nerurkar et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 295 citations

Life Sciences, Pharmacology, Physiology +17