Sarah E. Dowdell

Development of Dihydropyridone Indazole Amides as Selective Rho-Kinase Inhibitors

Krista Goodman, Haifeng Cui, Sarah E. Dowdell et al. · Journal of Medicinal Chemistry · 2006 · 154 citations · Full text

Indazole Substitution, Medicinal Chemistry, Oral Bioavailability +11

Discovery of GSK2193874: An Orally Active, Potent, and Selective Blocker of Transient Receptor Potential Vanilloid 4

Mui Cheung, Weike Bao, David J. Behm et al. · ACS Medicinal Chemistry Letters · 2017 · 94 citations · Full text

Potent, Selective and Orally Bioavailable Dihydropyrimidine Inhibitors of Rho Kinase (ROCK1) as Potential Therapeutic Agents for Cardiovascular Diseases

Clark A. Sehon, Gren Z. Wang, Andrew Q. Viet et al. · Journal of Medicinal Chemistry · 2008 · 72 citations · Full text

Medicinal Chemistry, Potential Therapeutic Agents, Biochemistry +15

Discovery of Aminofurazan-azabenzimidazoles as Inhibitors of Rho-Kinase with High Kinase Selectivity and Antihypertensive Activity

Robert A. Stavenger, Haifeng Cui, Sarah E. Dowdell et al. · Journal of Medicinal Chemistry · 2006 · 71 citations · Full text

Drug Target, Bioorganic Chemistry, Pharmacotherapy +18

Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors

Krista Goodman, Michael J. Bury, Mui Cheung et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 52 citations · Full text

Pharmaceutical Science, Medicine, Drug Development +3