Krista Goodman

An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure

Kevin S. Thorneloe, Mui Cheung, Weike Bao et al. · Science Translational Medicine · 2012 · 336 citations

Medicine, Cardiology, Pharmacotherapy +10

Development of Dihydropyridone Indazole Amides as Selective Rho-Kinase Inhibitors

Krista Goodman, Haifeng Cui, Sarah E. Dowdell et al. · Journal of Medicinal Chemistry · 2006 · 156 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Discovery of GSK2193874: An Orally Active, Potent, and Selective Blocker of Transient Receptor Potential Vanilloid 4

Mui Cheung, Weike Bao, David J. Behm et al. · ACS Medicinal Chemistry Letters · 2017 · 99 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation

Gregory J. Gatto, Zhaohui Ao, Michael G. Kearse et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2011 · 73 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Potent, Selective and Orally Bioavailable Dihydropyrimidine Inhibitors of Rho Kinase (ROCK1) as Potential Therapeutic Agents for Cardiovascular Diseases

Clark A. Sehon, Gren Z. Wang, Andrew Q. Viet et al. · Journal of Medicinal Chemistry · 2008 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13