<i>DCLRE1C</i>(ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency

Timo Volk, Ulrich Pannicke, İsmail Reisli, +23

Human Molecular Genetics

Impact of a 3-Months Vegetarian Diet on the Gut Microbiota and Immune Repertoire

Chenchen Zhang, Andrea Björkman, Kaiye Cai, +10

Frontiers in Immunology

XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency

Chaowan Guo, Yuka Nakazawa, Lisa Woodbine, +13

Journal of Allergy and Clinical Immunology

Primary ImmunodeficiencyAutoimmune DiseaseImmunodeficienciesImmunologyPathology +9

Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesis

Likun Du, Roujun Peng, Andrea Björkman, +17

The Journal of Experimental Medicine

Lymphoid NeoplasiaImmunogeneticsGenome InstabilityAutoimmune DiseaseDna Double-strand Break +13

A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination

Elin Enervald, Likun Du, Torkild Visnes, +17

The Journal of Experimental Medicine

GeneticsImmunologyGenomic MechanismImmunodominanceMolecular Biology +21

Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution

Andrea Björkman, Søren L. Johansen, Lin Lin, +10

Genes & Development

Polδ Subunit Poldip3GeneticsR-loop ResolutionMolecular BiologyTranscriptional Regulation +15

DNA-PKcs Is Involved in Ig Class Switch Recombination in Human B Cells

Andrea Björkman, Likun Du, Kerstin Felgentreff, +9

The Journal of Immunology

ChromatinGenome InstabilityCell RegulationHuman B CellsImmune Cell Development +12

Mutations That Affect Ligand Binding to the Escherichia coli Aspartate Receptor

Andrea Björkman, Pete Dunten, Mats Sandgren, +2

Journal of Biological Chemistry

Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET

Dimitris C. Kanellis, Asimina Zisi, Zdeněk Škrott, +12

Cell Death and Differentiation

Disulfiram Metabolite CuetChemoprevention StrategyP53 ProteinActionable Cancer VulnerabilityCancer Biology +16

Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells

Andrea Björkman, Per Qvist, Likun Du, +6

Proceedings of the National Academy of Sciences