Marilyn Grous

1,4-Cyclohexanecarboxylates:  Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma

Siegfried B. Christensen, Aimee M. Guider, Cornelia J. Forster et al. · Journal of Medicinal Chemistry · 1998 · 150 citations · Full text

Suppression of human inflammatory cell function by subtype‐selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B

Carol D. Manning, Miriam Burman, Siegfried B. Christensen et al. · British Journal of Pharmacology · 1999 · 143 citations · Full text

Inflammation, Anti-inflammatory, Subtype‐selective Pde4 Inhibitors +10

SB 207499 (Ariflo), a Potent and Selective Second-Generation Phosphodiesterase 4 Inhibitor: In Vitro Anti-inflammatory Actions

Mary S. Barnette, S. Brøgger Christensen, David M. Essayan et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 140 citations

Inhibitors of phosphodiesterase IV (PDE IV) increase acid secretion in rabbit isolated gastric glands: correlation between function and interaction with a high-affinity rolipram binding site.

Mary S. Barnette, Marilyn Grous, L B Cieslinski et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 105 citations

SB 207499 (Ariflo), a second generation phosphodiesterase 4 inhibitor, reduces tumor necrosis factor alpha and interleukin-4 production in vivo.

Don E. Griswold, Edward F. Webb, Alison M. Badger et al. · PubMed · 1998 · 86 citations

Inflammation, Cytokine, Anti-inflammatory +13