Jing-Ruey Joanna Yeh

Engineered CRISPR-Cas9 nucleases with altered PAM specificities

Benjamin P. Kleinstiver, Michelle S. Prew, Shengdar Q. Tsai et al. · Nature · 2015 · 1.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)

Jeffry D. Sander, Elizabeth J. Dahlborg, Mathew J. Goodwin et al. · Nature Methods · 2010 · 518 citations · Full text

Life Sciences, Biomolecular Engineering, Molecular Biology +14

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion

Kensuke Tateishi, Hiroaki Wakimoto, A. John Iafrate et al. · Cancer Cell · 2015 · 445 citations · Full text

Medicine, Cancer Biology, Oncology +16

Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System

Woong Y. Hwang, Yanfang Fu, Deepak Reyon et al. · PLoS ONE · 2013 · 378 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

A Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort

Eugene P. Rhee, Jennifer E. Ho, Ming‐Huei Chen et al. · Cell Metabolism · 2013 · 337 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15